Search on: GRAND MAL SEIZURE DISORDER 
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Descriptor English:   Epilepsy, Tonic-Clonic 
Descriptor Spanish:   Epilepsia Tónico-Clónica 
Descriptor Portuguese:   Epilepsia Tônico-Clônica 
Synonyms English:   Epilepsy, Grand Mal
Epilepsy, Major
Grand Mal Seizure Disorder
Major Motor Seizure Disorder
Seizure Disorder, Tonic Clonic  
Tree Number:   C10.228.140.490.375.290
Definition English:   A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329) 
Indexing Annotation English:   do not confuse with EPILEPSY, TONIC see EPILEPSY, GENERALIZED
History Note English:   1992(1963) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   30330 
Unique Identifier:   D004830 

Occurrence in VHL:
 

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